Intestinal absorption and biliary elimination of glycyrrhizic acid diethyl ester in rats
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چکیده
منابع مشابه
Intestinal absorption and biliary elimination of glycyrrhizic acid diethyl ester in rats
BACKGROUND The purpose of this study was to evaluate absorption and elimination from the gastrointestinal tract of glycyrrhizic acid diethyl ester (GZ-DE) which was prepared as a prodrug of glycyrrhizic acid (a poorly absorbed compound) in rats. METHODS After the GZ-DE solution was administered via the intravenous, intraduodenal, intraileal, and stomach routes, GZ-DE and GZ concentrations in ...
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متن کاملintestinal zinc absorption in desferroxamine-treated rats
desferroxamine (desferal) is used tochelate iron in thalassemia, a disease of very high prevalence in various parts of lran. we have investigated intestinal zinc absorption in desferal-treated rats which, in pilot experiments, showed low serum levels of both iron and zinc. intraperitoneal administration of ten 0.5 g doses of desferal (one injection every other day) to male rats produced severe ...
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ژورنال
عنوان ژورنال: Drug Design, Development and Therapy
سال: 2013
ISSN: 1177-8881
DOI: 10.2147/dddt.s51638